2015 Samuel Szabo Pediatric Oncology Term Fellow Research Award

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2015 Samuel Szabo Pediatric Oncology Term Fellow Research Award

In October 2015, the Samuel Szabo Foundation donated $15,000 to Huang Lab and the Angie Fowler AYA Cancer Institute at University Rainbow Babies & Children's Hospital for the Samuel Szabo Pediatric Oncology Term Fellow Research Award. This award was established in 2014 to further our mission to fund research for childhood cancers. We would like to thank all our supporters for their generosity!  

From Dr. Alex Y. Huang, MD,PhD, Clinical Pediatric Hematology-Oncology Fellowship Program Director at Case Western Reserve University Medical Center, "I want to sincerely thank you and the Samuel Szabo Foundation for your partnership in reaching the goal of achieving a cure for every child facing a diagnosis of cancer. The generosity of you, the foundation and supporters is a tremendous source of inspiration and motivation for all of us in the Huang Lab and the Angie Fowler AYA Cancer Institute at UH Rainbow Babies & Children's Hospital. Through the funding support of the Samuel Szabo Foundation, we were able to began a series of studies to identify a new protein called Cdk5 in leukemia cells that may be targeted for new therapy. The same protein was also found to be important for the development of graft-versus-host disease, a devastating consequence of bone marrow transplant procedures that are often used to treat aggressive leukemia and other childhood cancers and non-malignant diseases. These studies are being conducted by Dr. Anant Vatsayan, MD, a senior Pediatric Hematology-Oncology Fellow in my lab who aspires to be a pediatric bone marrow transplant specialist. Another study, carried out by Dr. David Askew, PhD in my laboratory with the support of the Samuel Szabo Foundation, investigates how the same protein can be targeted in T-cell acute lymphoblastic leukemia (T-cell ALL), a particularly aggressive leukemia affecting children and adolescent populations. The pilot studies performed with the support of the foundation has now enable us to obtain national foundation grants ($100,000 research grant from the St. Baldrick's Foundation, and a $275,000 grant from the National Cancer Institute at the NIH; both in 2015) to further our finding. None of this would be possible without the generosity of supporters of the Samuel Szabo Foundation."